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Dimerization

(chemistry) A chemical reaction in which two identical molecular entities react to form a single dimer.
The chemical union of two identical molecules.
verb: to react or cause to react to form a dimer.

The reverse of dimerization is often called dissociation. Wikipedia


Dimerization as a regulatory mechanism in signal transduction.

Dynamic protein-protein interactions are a key component of biological regulatory networks. Dimerization events - physical interactions between related proteins - represent an important subset of protein-protein interactions and are frequently employed in transducing signals from the cell surface to the nucleus. Importantly, dimerization between different members of a protein family can generate considerable functional diversity when different protein combinations have distinct regulatory properties. A survey of processes known to be controlled by dimerization illustrates the diverse physical and biological outcomes achieved through this regulatory mechanism. These include: facilitated proximity and orientation; differential regulation by heterodimerization; generation of temporal and spatial boundaries; enhancement of specificity; and regulated monomer - to - dimer transitions. Elucidation of these mechanisms has led to the design of new approaches to study and to manipulate signal transduction pathways. http://www.ncbi.nlm.nih.gov/pubmed/9597142

See Also


8.12 - Law of Attraction
9.4 - Law of Attraction
Aggregation
Assimilation
Association
Bjerknes Effect
Concentration
Dimer
Dispersion
Dissociation
Law of Attraction
Law of Attraction and Repulsion
Negative Entropy
Quantum Entanglement
Sympathetic Association
Sympathetic Oscillation
Sympathetic Vibration
Syntropy

Created by Dale Pond. Last Modification: Thursday May 24, 2012 07:49:27 MDT by Dale Pond.